Tannin content of English walnuts : thesis ...

Present methods for the production of leather from animal hides still depend from the most part on the use of natural tannin extracts. During the year, 1952, the amount of natural tannin extracts used by the leather industry was 560,452,119 pounds as compared to 35,793,000 pounds of synthetic tanning materials. It is not as yet possible to produce synthetic materials as economically as the natural extracts; the result being that there is still a very great demand for natural tannin extracts. The need for finding new domestic sources of tannins is apparent when the amounts of domestic and imported extracts are compared. During the period 1940-1950, only 744,394,560 pounds of natural tannin extracts were produced domestically as compared to 1,579,244,280 pounds of tannin extracts which were imported. Tannins are known to occur in various parts of plants and they are also known to occur in the majority of the members of the plant kingdom. The purpose of this research is to investigate the feasibility of utilizing parts of the walnut tree as a source of tannins

CMB Polarization: Scientific Case and Data Analysis Issues

We review the science case for studying CMB polarization. We then discuss the main issues related to the analysis of forth-coming polarized CMB data, such as those expected from balloon-borne (e.g. BOOMERanG) and satellite (e.g. Planck) experiments.Comment: 6 pages, 4 figures. To appear in "Astrophysical Polarized Background" Workshop Proceedings, eds. S. Cecchini, S. Cortiglioni, R. Sault and C. Sbarra, AIP, in pres

ROMA: a map-making algorithm for polarised CMB data sets

We present ROMA, a parallel code to produce joint optimal temperature and polarisation maps out of multidetector CMB observations. ROMA is a fast, accurate and robust implementation of the iterative generalised least squares approach to map-making. We benchmark ROMA on realistic simulated data from the last, polarisation sensitive, flight of BOOMERanG.Comment: Accepted for publication in Astronomy & Astrophysics. Version with higher quality figures available at http://www.fisica.uniroma2.it/~cosmo/ROM

Correlated Component Analysis for diffuse component separation with error estimation on simulated Planck polarization data

We present a data analysis pipeline for CMB polarization experiments, running from multi-frequency maps to the power spectra. We focus mainly on component separation and, for the first time, we work out the covariance matrix accounting for errors associated to the separation itself. This allows us to propagate such errors and evaluate their contributions to the uncertainties on the final products.The pipeline is optimized for intermediate and small scales, but could be easily extended to lower multipoles. We exploit realistic simulations of the sky, tailored for the Planck mission. The component separation is achieved by exploiting the Correlated Component Analysis in the harmonic domain, that we demonstrate to be superior to the real-space application (Bonaldi et al. 2006). We present two techniques to estimate the uncertainties on the spectral parameters of the separated components. The component separation errors are then propagated by means of Monte Carlo simulations to obtain the corresponding contributions to uncertainties on the component maps and on the CMB power spectra. For the Planck polarization case they are found to be subdominant compared to noise.Comment: 17 pages, accepted in MNRA

A novel CMB polarization likelihood package for large angular scales built from combined WMAP and Planck LFI legacy maps

We present a CMB large-scale polarization dataset obtained by combining WMAP Ka, Q and V with Planck 70 GHz maps. We employ the legacy frequency maps released by the WMAP and Planck collaborations and perform our own Galactic foreground mitigation technique, which relies on Planck 353 GHz for polarized dust and on Planck 30 GHz and WMAP K for polarized synchrotron. We derive a single, optimally-noise-weighted, low-residual-foreground map and the accompanying noise covariance matrix. These are shown, through $\chi^2$ analysis, to be robust over an ample collection of Galactic masks. We use this dataset, along with the Planck legacy Commander temperature solution, to build a pixel-based low-resolution CMB likelihood package, whose robustness we test extensively with the aid of simulations, finding excellent consistency. Using this likelihood package alone, we constrain the optical depth to reionazation $\tau=0.069^{+0.011}_{-0.012}$ at $68\%$ C.L., on 54\% of the sky. Adding the Planck high-$\ell$ temperature and polarization legacy likelihood, the Planck lensing likelihood and BAO observations we find $\tau=0.0714_{-0.0096}^{+0.0087}$ in a full $\Lambda$CDM exploration. The latter bounds are slightly less constraining than those obtained employing \Planck\ HFI CMB data for large angle polarization, that only include EE correlations. Our bounds are based on a largely independent dataset that does include also TE correlations. They are generally well compatible with Planck HFI preferring slightly higher values of $\tau$. We make the low-resolution Planck and WMAP joint dataset publicly available along with the accompanying likelihood code.Comment: The WMAP+LFI likelihood module is available on \http://www.fe.infn.it/u/pagano/low_ell_datasets/wmap_lfi_legacy

Group I metabotropic glutamate receptors activate burst firing in rat midbrain dopaminergic neurons

We have investigated the changes in the spontaneous firing pattern induced by DHPG ((S)-3,5-dihydroxyphenylglycine) and NMDA (N-methyl-d-aspartic acid) on rat dopaminergic neurons in substantia nigra pars compacta (SNc) using sharp microelectrode recordings in in vitro conditions. Twenty-five out of 33 cells modified the regular single-pacemaker activity in burst firing when exposed to the Group I metabotropic glutamate receptor (mGluR) agonist DHPG (30 muM) and d-tubocurarine (500 muM) (d-TC), whereas they all fired in bursts during NMDA (20 muM) plus d-TC application. The blockade of SK-channels by d-TC and apamin was essential for the production of both types of bursts. Although the two drugs induced a similar number of action potentials per burst, the DHPG-induced bursts had a lower frequency, a longer duration and a longer plateau period without spikes. In addition, the DHPG-induced bursting had a longer wash-out, could be reduced or blocked by the mGluR I selective, non-competitive antagonist CPCCOEt (7-cyclopropan[b]chromen-1a-carboxylic acid ethyl ester) (100 muM) while it was not affected by the mGluR 5 selective antagonist MPEP (2-methyl-6-(phenylethynyl)-pyridine (10 muM). These results suggest that both the activation of glutamate metabotropic type I and NMDA ionotropic receptors induce burst firing in the dopaminergic cells of the ventral midbrain when the activity of the SK-channels is reduced. (C) 2002 Elsevier Science Ltd. All rights reserved

CMB Power Spectrum Estimation for the Planck Surveyor

We use an iterative generalized least squares map-making algorithm, in conjunction with Monte Carlo techniques, to obtain estimates of the angular power spectrum from cosmic microwave background (CMB) maps. This is achieved by characterizing and removing the instrumental noise contribution in multipole space. This technique produces unbiased estimates and can be applied to an arbitrary experiment. In this paper, we use it on realistic simulations of Planck Low Frequency Instrument (LFI) observations, showing that it can lead to fast and reliable estimation of the CMB angular power spectrum from megapixel maps.Comment: 6 pages, 5 figures. Matching accepted versio

The challenge of perioperative pain management in opioid-tolerant patients

The increasing number of opioid users among chronic pain patients, and opioid abusers among the general population, makes perioperative pain management challenging for health care professionals. Anesthesiologists, surgeons, and nurses should be familiar with some pharmacological phenomena which are typical of opioid users and abusers, such as tolerance, physical dependence, hyperalgesia, and addiction. Inadequate pain management is very common in these patients, due to common prejudices and fears. The target of preoperative evaluation is to identify comorbidities and risk factors and recognize signs and symptoms of opioid abuse and opioid withdrawal. Clinicians are encouraged to plan perioperative pain medications and to refer these patients to psychiatrists and addiction specialists for their evaluation. The aim of this review was to give practical suggestions for perioperative management of surgical opioid-tolerant patients, together with schemes of opioid conversion for chronic pain patients assuming oral or transdermal opioids, and patients under maintenance programs with methadone, buprenorphine, or naltrexone

A Map-Making Algorithm for the Planck Surveyor

We present a parallel implementation of a map-making algorithm for CMB anisotropy experiments which is both fast and efficient. We show for the first time a Maximum Likelihood, minimum variance map obtained by processing the entire data stream expected from the Planck Surveyor, under the assumption of a symmetric beam profile. Here we restrict ourselves to the case of the 30 GHz channel of the Planck Low Frequency Instrument. The extension to Planck higher frequency channels is straightforward. If the satellite pointing periodicity is good enough to average data that belong to the same sky circle, then the code runs very efficiently on workstations. The serial version of our code also runs on very competitive time-scales the map-making pipeline for current and forthcoming balloon borne experiments.Comment: 11 pages, 10 figures. Reflects accepted A&A versio

Thermal Approaches to Interpret Laser Damage Experiments

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